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August 21, 2006

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Filed : 9:00 pm

Dieting - Topix.net
News on Dieting continually updated from thousands of sources around the net. (more…)

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Proinflammatory cytokine production and insulin sensitivity regulated by overexpression of resistin in 3T3-L1 adipocytes
Resistin is secreted from adipocytes, and high circulating levels have been associated with obesity and insulin resistance. To investigate whether resistin could exert autocrine effects in adipocytes, we expressed resistin gene in 3T3-L1 fibroblasts using a lentiviral vector, and selected several stably-transduced cell lines under blasticidin selection.We observed that 3T3-L1 adipocytes expressing resistin have a decreased gene expression for related transcriptional factors (CCAAT/enhancer binding protein ?(C/EBP?) , peroxisome proliferator-activated receptor gamma (PPAR?), and adipocyte lipid binding protein (ALBP/aP2) which is one of target genes for the PPAR? during adipocyte differentiation,. Overexpression of resistin increased the levels of three proinflammatory cytokines, tumor necrosis factor alpha (TNF?), interleukin 6 (IL-6) and monocyte chemoattractant protein-1 (MCP-1), which play important roles for insulin resistance, glucose and lipid metabolisms during adipogenesis. Furthermore, overexpressing resistin in adipocytes inhibits glucose transport 4 (GLUT4) activity and its gene expression, reducing insulin’s ability for glucose uptake by 30 %.In conclusion, resistin overexpression in stably transduced 3T3-L1 cells resulted in: 1) Attenuation of programmed gene expression responsible for adipogenesis; 2) Increase in expression of proinflammatory cytokines; 3) Decrease in insulin responsiveness of the glucose transport system. These data suggest a new role for resistin as an autocrine/paracrine factor affecting inflammation and insulin sensitivity in adipose tissue. (more…)

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Copper in high-fat diet risks mental decline
Elderly people whose diets were rich in copper and heavy in saturated fats and trans fats risked faster mental decline that could be related to the onset of Alzheimer’s disease , researchers said on Monday. (more…)

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Filed : 12:45 pm

Is Your Diet Colorblind?
Next time you have a meal, look at your plate - what colors do you see? If its mostly white and brown then your diet might be colorblind! (more…)

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The Dynamic Growth of Organic Private Label Products
In an age of packaging, the marketing of a product largely determine its commercial success. Along with nationalized industries, commercial establishments owned by private owners are gradually capturing the modern market with their diverse products. In an era where an increasing number of people are gradually becoming more and more health conscious and overall well being, food materials consumed as part of the daily diet and occasional treats are increasingly being subjected to minute and extreme scrutiny by a large section of the present day consumer circle. While in older times, taste and constituent ingredients of a food preparation were given maximum priorities, today, the focus has shifted to how healthy and beneficial the food ingredients are. Because of these various reasons, along with readymade commercial food products, food products containing organic ingredients are today being made available in most metropolitans. Mostly used directly in their natural forms without being modified in any way by external additives, these organic Food Ingredients have a higher concentration of undiluted food nutrients and are therefore, considered purer in nature. Agcommoditiesinc.com informs you on some of the major types of organic ingredients commercialized today and made available at select Private Label foods outlets. (more…)

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